Erratum to: Pig lacks functional NLRC4 and NAIP genes
نویسندگان
چکیده
منابع مشابه
Down with doublespeak: NAIP/NLRC4 inflammasomes get specific
The NAIP family members are cytosolic pattern recognition receptors that detect the activity of bacterial type III secretion systems (T3SSs) when they aberrantly translocate one of three NAIP ligands. Mouse NAIP1 and NAIP2 bind the T3SS needle and rod proteins, whereas NAIP5 and NAIP6 bind flagellin. T4SSs are also detected when they cause flagellin to enter the cytosol. Upon interaction with i...
متن کاملBroad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome.
Inflammasomes are cytosolic multiprotein complexes that initiate host defense against bacterial pathogens by activating caspase-1-dependent cytokine secretion and cell death. In mice, specific nucleotide-binding domain, leucine-rich repeat-containing family, apoptosis inhibitory proteins (NAIPs) activate the nucleotide-binding domain, leucine-rich repeat-containing family, CARD domain-containin...
متن کاملSMN1 and NAIP genes deletions in different types of spinal muscular atrophy in Khuzestan province, Iran
Background: Spinal muscular atrophy (SMA) is the second most common lethal autosomal recessive disease. It is a neuromuscular disorder caused by degenerative of lower motor neurons and occasionally bulbar neurons leading to progressive limb paralysis and muscular atrophy. The SMN1 gene is recognized as a SMA causing gene while NAIP has been characterized as a modifying factor for the clinical ...
متن کاملInnate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
Inflammasomes are a family of cytosolic multiprotein complexes that initiate innate immune responses to pathogenic microbes by activating the caspase 1 protease. Although genetic data support a critical role for inflammasomes in immune defence and inflammatory diseases, the molecular basis by which individual inflammasomes respond to specific stimuli remains poorly understood. The inflammasome ...
متن کاملErratum Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation
Victor Kirik, Myeong Min Lee, Katja Wester, Ullrich Herrmann, Zhengui Zheng, David Oppenheimer, John Schiefelbein and Martin Hulskamp Development 132, 1477-1485. The e-press version of the article that was published on the 23rd February contains the incorrect acceptance date. The correct date is 19 January 2005 Both the published print and online versions of this article are correct. We apologi...
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ژورنال
عنوان ژورنال: Immunogenetics
سال: 2016
ISSN: 0093-7711,1432-1211
DOI: 10.1007/s00251-016-0963-5